• The evolution of surgical glaucoma treatment has led to the development of procedures attempting to achieve better efficacy, but having variable complication profiles • MIGS devices have the capacity to provide efficacy and reduce complications with rapid patient recovery • The HYDRUS Microstent has a Tri-Modal® mechanism of action that bypasses the trabecular meshwork, scaffolds Schlemm’s canal, and spans approximately 90° ensuring access to collector channels in the nasal region • The pivotal clinical data demonstrate that combining the HYDRUS Microstent with cataract surgery provides a durable decrease in IOP in adults with mild to moderate primary open-angle glaucoma with a concurrent decrease in medication dependence